InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc6a20b

Summary

InnateDB Protein

IDBP-206367.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc6a20b

Protein Name

solute carrier family 6 (neurotransmitter transporter), member 20B

Synonyms

AA986306; Sit1; Slc6a20; XT3; Xtrp3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026273

InnateDB Gene

IDBG-206365 (Slc6a20b)

Protein Structure

UniProt Annotation

Function

Does not show transporter activity with a range of tested amino acids including proline, glutamine, glutamic acid, leucine, alanine, histidine, glycine and arginine. {ECO:0000269PubMed:15689184}.

Subcellular Localization

Apical cell membrane {ECO:0000269PubMed:16174864}; Multi-pass membrane protein {ECO:0000269PubMed:16174864}. Note=Located in the apical brush border membrane of kidney proximal tubule cells.

Disease Associations

Tissue Specificity

Detected only in kidney and lung. {ECO:0000269PubMed:15689184, ECO:0000269PubMed:9932288}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005328	neurotransmitter:sodium symporter activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006836	neurotransmitter transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane