InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adra1d

Summary

InnateDB Protein

IDBP-207144.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Adra1d

Protein Name

adrenergic receptor, alpha 1d

Synonyms

[a]1d; Adra-1; Adra1; Adra1a; alpha1D-AR; Gpcr8; Spr8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099473

InnateDB Gene

IDBG-207140 (Adra1d)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004937	alpha1-adrenergic receptor activity

Biological Process

GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0007186	G-protein coupled receptor signaling pathway
GO:0071875	adrenergic receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:106673

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000363 Alpha 1D adrenoceptor
IPR002233 Adrenoceptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00237
PR00240
PR01103

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite