Version 5.4
Mus musculus Protein: Itpkb
Summary
InnateDB Protein IDBP-207163.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Itpkb
Protein Name inositol 1,4,5-trisphosphate 3-kinase B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000069851
InnateDB Gene IDBG-207161 (Itpkb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity
Biological Process
GO:0000165 MAPK cascade
GO:0007166 cell surface receptor signaling pathway
GO:0030217 T cell differentiation
GO:0045059 positive thymic T cell selection
GO:0045061 thymic T cell selection
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046638 positive regulation of alpha-beta T cell differentiation
Cellular Component
Protein Structure and Domains
PDB ID MGI:109235
InterPro IPR005522 Inositol polyphosphate kinase
PFAM PF03770
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q8BKB2
TrEMBL Q8BKB2
UniProt Splice Variant
Entrez Gene 320404
UniGene Mm.132535
RefSeq NP_001074644
MGI ID 2AQX
MGI Symbol Itpkb
OMIM
CCDS CCDS35808
HPRD
IMGT
EMBL AC121838 AK053759 BC151160 BC157986 BC158000 CH466555
GenPept AAI51161 AAI57987 AAI58001 BAC35509 EDL13155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca