Version 5.4
Mus musculus Protein: Cds2
Summary
InnateDB Protein IDBP-207333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cds2
Protein Name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
Synonyms 5730450N06Rik; 5730460C18Rik; AI854580; D2Wsu127e;
Species Mus musculus
Ensembl Protein ENSMUSP00000099470
InnateDB Gene IDBG-207331 (Cds2)
Protein Structure
UniProt Annotation
Function Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004605 phosphatidate cytidylyltransferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007602 phototransduction
GO:0008152 metabolic process
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0070085 glycosylation
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1332236
InterPro IPR000374 Phosphatidate cytidylyltransferase
IPR016720 Phosphatidate cytidylyltransferase, eukaryota
PFAM PF01148
PRINTS
PIRSF PIRSF018269
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99L43
PhosphoSite PhosphoSite-Q99L43
TrEMBL Q6PBC0
UniProt Splice Variant
Entrez Gene 110911
UniGene Mm.464431
RefSeq NP_619592
MGI ID
MGI Symbol Cds2
OMIM
CCDS CCDS16772
HPRD
IMGT
EMBL AK036328 AK147541 AK166001 AK170888 AL807793 AY159802 BC003852 BC059776 BC069879
GenPept AAH03852 AAH59776 AAH69879 AAO17790 BAC29384 BAE27984 BAE38511 BAE42095

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca