InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nvl

Summary

InnateDB Protein

IDBP-207458.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nvl

Protein Name

nuclear VCP-like

Synonyms

1200009I24Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027797

InnateDB Gene

IDBG-207456 (Nvl)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:21474449}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0009378	four-way junction helicase activity
GO:0016301	kinase activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0008150	biological_process
GO:0008152	metabolic process

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0016235	aggresome

Protein Structure and Domains

PDB ID

MGI:1914709

InterPro

IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR008824 DNA helicase, Holliday junction RuvB type, N-terminal
IPR010488 Zeta toxin domain
IPR011704 ATPase, dynein-related, AAA domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00004
PF07724
PF13304
PF05496
PF06414
PF07728

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DBY8