Version 5.4
Mus musculus Gene: Nvl
Summary
InnateDB Gene IDBG-207456.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nvl
Gene Name nuclear VCP-like
Synonyms 1200009I24Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000026516
Encoded Proteins
IDBP-207458
nuclear VCP-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143748:
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:181093423-181144157
Strand Reverse strand
Band H4
Transcripts
ENSMUST00000027797 ENSMUSP00000027797
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016301 kinase activity
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016235 aggresome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143748
View Gene Order
ENSBTAG00000006718
Not yet available
Cross-References
SwissProt Q9DBY8
TrEMBL Q9CRW9
UniProt Splice Variant
Entrez Gene 67459
UniGene Mm.263464
RefSeq NM_026171 XM_006496964 XM_006496966
OMIM
CCDS CCDS15581
HPRD
IMGT
MGI ID MGI:1914709
MGI Symbol Nvl
EMBL AK004676 AK013982 AK054502 AK140509 BC031847
GenPept AAH31847 BAB23464 BAB29099 BAC35806 BAE24409
RNA Seq Atlas 67459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca