InnateDB Protein
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IDBP-207543.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Crls1
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Protein Name
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cardiolipin synthase 1
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Synonyms
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0610009I22Rik; 4930557M15Rik; 5730490M08Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000028835
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InnateDB Gene
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IDBG-207541 (Crls1)
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Protein Structure
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Function |
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
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Subcellular Localization |
Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0003674
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molecular_function
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GO:0016780
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phosphotransferase activity, for other substituted phosphate groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1913836
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InterPro |
IPR000462
CDP-alcohol phosphatidyltransferase
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PFAM |
PF01066
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q80ZM8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
66586
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UniGene |
|
RefSeq |
NP_001019556
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MGI ID |
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MGI Symbol |
Crls1
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OMIM |
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CCDS |
CCDS16779
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HPRD |
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IMGT |
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EMBL |
AK016165
BC048702
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GenPept |
AAH48702
BAB30134
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