Mus musculus Protein: Bpnt1
Summary
InnateDB Protein IDBP-207997.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bpnt1
Protein Name bisphosphate 3'-nucleotidase 1
Synonyms BPntase;
Species Mus musculus
Ensembl Protein ENSMUSP00000027916
InnateDB Gene IDBG-207995 (Bpnt1)
Protein Structure
UniProt Annotation
Function Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4- trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity
GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity
Biological Process
GO:0016311 dephosphorylation
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0005575 cellular_component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1338800
InterPro IPR000760 Inositol monophosphatase
PFAM PF00459
PRINTS PR00377
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z0S1
PhosphoSite PhosphoSite-Q9Z0S1
TrEMBL D3Z5X0
UniProt Splice Variant
Entrez Gene 23827
UniGene Mm.405394
RefSeq NP_035924
MGI ID
MGI Symbol Bpnt1
OMIM
CCDS CCDS15597
HPRD
IMGT
EMBL AC129195 AF125043 AK008714 AK151931 AK152009 BC011036
GenPept AAD17330 AAH11036 BAB25850 BAE30807 BAE30872