InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kcnk2

Summary

InnateDB Protein

IDBP-208387.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Kcnk2

Protein Name

potassium channel, subfamily K, member 2

Synonyms

A430027H14Rik; AI848635; TREK-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078416

InnateDB Gene

IDBG-208385 (Kcnk2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding
GO:0015271	outward rectifier potassium channel activity
GO:0019870	potassium channel inhibitor activity
GO:0022841	potassium ion leak channel activity

Biological Process

GO:0006813	potassium ion transport
GO:0007186	G-protein coupled receptor signaling pathway
GO:0030322	stabilization of membrane potential
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex

Protein Structure and Domains

PDB ID

MGI:109366

InterPro

IPR003092 Two pore domain potassium channel, TASK family
IPR003280 Two pore domain potassium channel
IPR003976 Two pore domain potassium channel, TREK
IPR008074 Two pore domain potassium channel, TRAAK
IPR013099 Two pore domain potassium channel domain

PFAM

PF07885

PRINTS

PR01095
PR01333
PR01499
PR01691

PIRSF

PIRSF038061

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt