Mus musculus Protein: Smurf1
Summary
InnateDB Protein IDBP-208408.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Smurf1
Protein Name SMAD specific E3 ubiquitin protein ligase 1
Synonyms 4930431E10Rik; mKIAA1625;
Species Mus musculus
Ensembl Protein ENSMUSP00000098029
InnateDB Gene IDBG-208404 (Smurf1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 227 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 227 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0016567 protein ubiquitination
GO:0030279 negative regulation of ossification
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1923038
InterPro IPR000008 C2 domain
IPR000569 HECT
IPR001202 WW domain
PFAM PF00168
PF00632
PF00397
PRINTS PR00360
PIRSF
SMART SM00239
SM00119
SM00456
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q4K9
UniProt Splice Variant
Entrez Gene 75788
UniGene Mm.402254
RefSeq NP_083714
MGI ID
MGI Symbol Smurf1
OMIM
CCDS CCDS39381
HPRD
IMGT
EMBL AC113295
GenPept