Version 5.4
Mus musculus Protein: Csrp2bp
Summary
InnateDB Protein IDBP-208476.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Csrp2bp
Protein Name cysteine and glycine-rich protein 2 binding protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000028911
InnateDB Gene IDBG-208472 (Csrp2bp)
Protein Structure
UniProt Annotation
Function Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly nuclear. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0016573 histone acetylation
GO:0043966 histone H3 acetylation
Cellular Component
GO:0005634 nucleus
GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1917264
InterPro IPR000182 GNAT domain
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CID0
PhosphoSite PhosphoSite-NP_001158285
TrEMBL E9QA90
UniProt Splice Variant
Entrez Gene 228714
UniGene Mm.490976
RefSeq NP_852082
MGI ID
MGI Symbol Csrp2bp
OMIM
CCDS CCDS16819
HPRD
IMGT
EMBL AL808123 BC031563
GenPept AAH31563 CAM26792

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca