InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wasf3

Summary

InnateDB Protein

IDBP-208833.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wasf3

Protein Name

WAS protein family, member 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000016143

InnateDB Gene

IDBG-208831 (Wasf3)

Protein Structure

UniProt Annotation

Function

Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003779	actin binding

Biological Process

GO:0007010	cytoskeleton organization
GO:0008360	regulation of cell shape
GO:0014003	oligodendrocyte development
GO:0030032	lamellipodium assembly
GO:0030036	actin cytoskeleton organization
GO:0031643	positive regulation of myelination