InnateDB Protein
|
IDBP-2091.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
SDF2L1
|
Protein Name
|
stromal cell-derived factor 2-like 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000248958
|
InnateDB Gene
|
IDBG-2089 (SDF2L1)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.
|
Disease Associations |
|
Tissue Specificity |
Ubiquitously expressed with high expression in testis, moderate expression in the pancreas, spleen, prostate, small intestine and colon. Very low expression is seen in brain and skeletal muscle. {ECO:0000269PubMed:11162531}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
11
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0034976
|
response to endoplasmic reticulum stress
|
GO:0042981
|
regulation of apoptotic process
|
GO:0071218
|
cellular response to misfolded protein
|
GO:0071712
|
ER-associated misfolded protein catabolic process
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR016093
MIR motif
|
PFAM |
PF02815
|
PRINTS |
|
PIRSF |
|
SMART |
SM00472
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9HCN8
|
PhosphoSite |
PhosphoSite-Q9HCN8
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
23753
|
UniGene |
|
RefSeq |
NP_071327
|
HUGO |
HGNC:10676
|
OMIM |
607551
|
CCDS |
CCDS13792
|
HPRD |
09614
|
IMGT |
|
EMBL |
AB043007
AF277316
AY359118
BC006248
BC132849
BC132851
CH471095
CR456570
|
GenPept |
AAI32850
AAI32852
AAK69113
AAQ89476
BAB18277
CAG30456
EAW59467
|
|
|