InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SDF2L1

Summary

InnateDB Protein

IDBP-2091.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SDF2L1

Protein Name

stromal cell-derived factor 2-like 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000248958

InnateDB Gene

IDBG-2089 (SDF2L1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.

Disease Associations

Tissue Specificity

Ubiquitously expressed with high expression in testis, moderate expression in the pancreas, spleen, prostate, small intestine and colon. Very low expression is seen in brain and skeletal muscle. {ECO:0000269PubMed:11162531}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	11 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0051087	chaperone binding
GO:0051117	ATPase binding
GO:0051787	misfolded protein binding

Biological Process

GO:0034976	response to endoplasmic reticulum stress
GO:0042981	regulation of apoptotic process
GO:0071218	cellular response to misfolded protein
GO:0071712	ER-associated misfolded protein catabolic process