InnateDB Protein
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IDBP-209325.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Sgca
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Protein Name
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sarcoglycan, alpha (dystrophin-associated glycoprotein)
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Synonyms
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50DAG; Asg;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000099451
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InnateDB Gene
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IDBG-209323 (Sgca)
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Protein Structure
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|
Function |
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
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Subcellular Localization |
Cell membrane, sarcolemma {ECO:0000269PubMed:9864373}; Single-pass type I membrane protein {ECO:0000269PubMed:9864373}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:9864373}.
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Disease Associations |
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Tissue Specificity |
Striated muscle, both skeletal and cardiac. {ECO:0000269PubMed:9196068}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
8
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:894698
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InterPro |
IPR006644
Dystroglycan-type cadherin-like
IPR008908
Sarcoglycan alphaepsilon
IPR015919
Cadherin-like
|
PFAM |
PF05510
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PRINTS |
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PIRSF |
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SMART |
SM00736
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TIGRFAMs |
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Modification |
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SwissProt |
P82350
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PhosphoSite |
PhosphoSite-P82350
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TrEMBL |
Q5SWB4
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UniProt Splice Variant |
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Entrez Gene |
20391
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UniGene |
Mm.406631
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RefSeq |
XP_006532705
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MGI ID |
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MGI Symbol |
Sgca
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OMIM |
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CCDS |
CCDS25266
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HPRD |
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IMGT |
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EMBL |
AB024920
AF019564
AF064081
AK075915
AL606480
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GenPept |
AAB70754
AAC33447
BAA83491
BAC36051
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