InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vsx1

Summary

InnateDB Protein

IDBP-209335.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vsx1

Protein Name

visual system homeobox 1 homolog (zebrafish)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039088

InnateDB Gene

IDBG-209333 (Vsx1)

Protein Structure

UniProt Annotation

Function

Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.

Disease Associations

Tissue Specificity

In the adult, expressed exclusively in the cells of the neural retina with expression restricted to postnatal cone bipolar interneurons.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007601	visual perception
GO:0042551	neuron maturation
GO:0048666	neuron development
GO:0050896	response to stimulus
GO:0060040	retinal bipolar neuron differentiation