InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ngfr

Summary

InnateDB Protein

IDBP-209610.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ngfr

Protein Name

nerve growth factor receptor (TNFR superfamily, member 16)

Synonyms

LNGFR; p75; p75NGFR; p75NTR; Tnfrsf16;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000000122

InnateDB Gene

IDBG-209608 (Ngfr)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005035	death receptor activity
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0048406	nerve growth factor binding

Biological Process

GO:0007165	signal transduction
GO:0007411	axon guidance
GO:0007417	central nervous system development
GO:0010468	regulation of gene expression
GO:0012501	programmed cell death
GO:0016048	detection of temperature stimulus
GO:0021675	nerve development
GO:0031069	hair follicle morphogenesis
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042488	positive regulation of odontogenesis of dentin-containing tooth
GO:0043588	skin development
GO:0048146	positive regulation of fibroblast proliferation
GO:0051799	negative regulation of hair follicle development
GO:2001235	positive regulation of apoptotic signaling pathway