Version 5.4
Mus musculus Protein: Gip
Summary
InnateDB Protein IDBP-209770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gip
Protein Name gastric inhibitory polypeptide
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000099446
InnateDB Gene IDBG-209768 (Gip)
Protein Structure
UniProt Annotation
Function Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005179 hormone activity
Biological Process
GO:0001101 response to acid
GO:0007565 female pregnancy
GO:0007613 memory
GO:0008344 adult locomotory behavior
GO:0009743 response to carbohydrate
GO:0009749 response to glucose
GO:0010269 response to selenium ion
GO:0010828 positive regulation of glucose transport
GO:0014070 response to organic cyclic compound
GO:0019233 sensory perception of pain
GO:0031018 endocrine pancreas development
GO:0031667 response to nutrient levels
GO:0032024 positive regulation of insulin secretion
GO:0033993 response to lipid
GO:0035640 exploration behavior
GO:0042493 response to drug
GO:0042594 response to starvation
GO:0043200 response to amino acid
GO:0043434 response to peptide hormone
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0048678 response to axon injury
GO:0050806 positive regulation of synaptic transmission
GO:0055123 digestive system development
GO:0060291 long-term synaptic potentiation
GO:0070094 positive regulation of glucagon secretion
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0034774 secretory granule lumen
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID MGI:107504
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48756
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 14607
UniGene
RefSeq NP_032145
MGI ID
MGI Symbol Gip
OMIM
CCDS CCDS25287
HPRD
IMGT
EMBL AK008308 AL603682 CH466556 U34295
GenPept AAC52731 BAB25592 CAM18267 EDL16005

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca