InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gip

Summary

InnateDB Gene

IDBG-209768.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gip

Gene Name

gastric inhibitory polypeptide

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000014351

Encoded Proteins

IDBP-209770

gastric inhibitory polypeptide

IDBP-209772

gastric inhibitory polypeptide

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159224:
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:96024545-96030831

Strand

Forward strand

Band

Transcripts

ENSMUST00000103157	ENSMUSP00000099446
ENSMUST00000103156	ENSMUSP00000099445

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005179	hormone activity

Biological Process

GO:0001101	response to acid
GO:0007565	female pregnancy
GO:0007613	memory
GO:0008344	adult locomotory behavior
GO:0009743	response to carbohydrate
GO:0009749	response to glucose
GO:0010269	response to selenium ion
GO:0010828	positive regulation of glucose transport
GO:0014070	response to organic cyclic compound
GO:0019233	sensory perception of pain
GO:0031018	endocrine pancreas development
GO:0031667	response to nutrient levels
GO:0032024	positive regulation of insulin secretion
GO:0033993	response to lipid
GO:0035640	exploration behavior
GO:0042493	response to drug
GO:0042594	response to starvation
GO:0043200	response to amino acid
GO:0043434	response to peptide hormone
GO:0043950	positive regulation of cAMP-mediated signaling
GO:0048678	response to axon injury
GO:0050806	positive regulation of synaptic transmission
GO:0055123	digestive system development
GO:0060291	long-term synaptic potentiation
GO:0070094	positive regulation of glucagon secretion
GO:0070328	triglyceride homeostasis