Version 5.4
Mus musculus Protein: Ube2z
Summary
InnateDB Protein IDBP-209807.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2z
Protein Name ubiquitin-conjugating enzyme E2Z (putative)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000098097
InnateDB Gene IDBG-209805 (Ube2z)
Protein Structure
UniProt Annotation
Function Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation (By similarity). {ECO:0000255PROSITE-ProRule:PRU00388}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0006915 apoptotic process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1343160
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF00179
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UE37
PhosphoSite PhosphoSite-Q3UE37
TrEMBL
UniProt Splice Variant
Entrez Gene 268470
UniGene Mm.38802
RefSeq NP_758504
MGI ID
MGI Symbol Ube2z
OMIM
CCDS CCDS36289
HPRD
IMGT
EMBL AK005524 AK077793 AK149770 AK153328 AK168942 AL603682 BC054412
GenPept AAH54412 BAB24097 BAC37014 BAE29074 BAE31907 BAE40750 CAM18270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca