Version 5.4
Mus musculus Gene: Ube2z
Summary
InnateDB Gene IDBG-209805.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2z
Gene Name ubiquitin-conjugating enzyme E2Z (putative)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000014349
Encoded Proteins
IDBP-209807
ubiquitin-conjugating enzyme E2Z (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159202:
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:96047432-96065388
Strand Reverse strand
Band D
Transcripts
ENSMUST00000100528 ENSMUSP00000098097
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0006915 apoptotic process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000159202
View Gene Order
ENSBTAG00000018802
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt Q3UE37
TrEMBL
UniProt Splice Variant
Entrez Gene 268470
UniGene Mm.38802
RefSeq NM_172300
OMIM
CCDS CCDS36289
HPRD
IMGT
MGI ID MGI:1343160
MGI Symbol Ube2z
EMBL AK005524 AK077793 AK149770 AK153328 AK168942 AL603682 BC054412
GenPept AAH54412 BAB24097 BAC37014 BAE29074 BAE31907 BAE40750 CAM18270
RNA Seq Atlas 268470

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca