InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pcgf2

Summary

InnateDB Protein

IDBP-210298.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Pcgf2

Protein Name

polycomb group ring finger 2

Synonyms

mel-18; Mel18; Rnf110; Zfp144;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099438

InnateDB Gene

IDBG-210296 (Pcgf2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Experimentally validated
Total	37 [view]
Protein-Protein	25 [view]
Protein-DNA	12 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0009952	anterior/posterior pattern specification
GO:0016573	histone acetylation
GO:0048704	embryonic skeletal system morphogenesis
GO:0048706	embryonic skeletal system development
GO:0070301	cellular response to hydrogen peroxide
GO:2001234	negative regulation of apoptotic signaling pathway

Cellular Component

GO:0001739	sex chromatin
GO:0005634	nucleus
GO:0016604	nuclear body
GO:0031519	PcG protein complex
GO:0035102	PRC1 complex

Protein Structure and Domains

PDB ID

MGI:99161

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B1AR14

UniProt Splice Variant

Entrez Gene

22658

UniGene

Mm.2418

RefSeq

MGI ID

MGI Symbol

Pcgf2

OMIM

CCDS

HPRD

IMGT

EMBL

AL596123

GenPept