Version 5.4
Mus musculus Protein: Pnmt
Summary
InnateDB Protein IDBP-210578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pnmt
Protein Name phenylethanolamine-N-methyltransferase
Synonyms Pent;
Species Mus musculus
Ensembl Protein ENSMUSP00000035549
InnateDB Gene IDBG-210576 (Pnmt)
Protein Structure
UniProt Annotation
Function Converts noradrenaline to adrenaline.
Subcellular Localization
Disease Associations
Tissue Specificity Brain (pons and medulla oblongata), adrenal gland and retina.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004603 phenylethanolamine N-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0042418 epinephrine biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID MGI:97724
InterPro IPR000940 Methyltransferase, NNMT/PNMT/TEMT
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF01234
PRINTS
PIRSF PIRSF000384
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40935
PhosphoSite PhosphoSite-P40935
TrEMBL Q0VB50
UniProt Splice Variant
Entrez Gene 18948
UniGene Mm.57030
RefSeq NP_032916
MGI ID
MGI Symbol Pnmt
OMIM
CCDS CCDS25347
HPRD
IMGT
EMBL BC119079 BC120789 CH466556 L12687
GenPept AAA68934 AAI19080 AAI20790 EDL16137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca