Version 5.4
Mus musculus Protein: Gss
Summary
InnateDB Protein IDBP-210632.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gss
Protein Name glutathione synthetase
Synonyms AI314904; GS-A/GS-B; GSH-S;
Species Mus musculus
Ensembl Protein ENSMUSP00000078630
InnateDB Gene IDBG-210630 (Gss)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004363 glutathione synthase activity
GO:0005524 ATP binding
GO:0016594 glycine binding
GO:0042277 peptide binding
GO:0042803 protein homodimerization activity
GO:0043295 glutathione binding
Biological Process
GO:0006750 glutathione biosynthetic process
GO:0007568 aging
GO:0009410 response to xenobiotic stimulus
GO:0031667 response to nutrient levels
GO:0034612 response to tumor necrosis factor
GO:0043200 response to amino acid
GO:0046686 response to cadmium ion
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:95852
InterPro IPR004887 Glutathione synthase, substrate-binding, eukaryotic
IPR005615 Glutathione synthase, eukaryotic
IPR016185 Pre-ATP-grasp domain
PFAM PF03199
PF03917
PRINTS
PIRSF PIRSF001558
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51855
PhosphoSite PhosphoSite-P51855
TrEMBL Q541E2
UniProt Splice Variant
Entrez Gene 14854
UniGene Mm.445833
RefSeq NP_032206
MGI ID
MGI Symbol Gss
OMIM
CCDS CCDS16951
HPRD
IMGT
EMBL AK146486 AK149577 AK169096 AL844852 AY079446 BC003784 CH466551 U35456
GenPept AAB09730 AAH03784 AAL87534 BAE27207 BAE28969 BAE40879 EDL06129 EDL06131

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca