Version 5.4
Mus musculus Protein: Cep250
Summary
InnateDB Protein IDBP-210747.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep250
Protein Name centrosomal protein 250
Synonyms AW490617; B230210E21Rik; Cep2; Inmp;
Species Mus musculus
Ensembl Protein ENSMUSP00000091988
InnateDB Gene IDBG-210743 (Cep250)
Protein Structure
UniProt Annotation
Function Probably plays an important role in centrosome cohesion during interphase. {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000269PubMed:16339073}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:16339073}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269PubMed:16339073}. Note=Component of the core centrosome where it is found at the proximal ends of centrioles. In photoreceptors, found at the proximal ends of basal bodies.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007049 cell cycle
Cellular Component
GO:0005814 centriole
GO:0005929 cilium
GO:0031616 spindle pole centrosome
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:108084
InterPro IPR009053 Prefoldin
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60952
PhosphoSite PhosphoSite-Q60952
TrEMBL
UniProt Splice Variant
Entrez Gene 16328
UniGene Mm.288729
RefSeq NP_796191
MGI ID
MGI Symbol Cep250
OMIM
CCDS CCDS50771
HPRD
IMGT
EMBL AK045557 AK139187 AL833786 BC057582 DQ148475 U33198
GenPept AAB41824 AAH57582 ABA29340 BAC32417 BAE23916

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca