InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Chd6

Summary

InnateDB Protein

IDBP-211678.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Chd6

Protein Name

chromodomain helicase DNA binding protein 6

Synonyms

5430439G14Rik; 6330406J24Rik; CHD-6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042291

InnateDB Gene

IDBG-211676 (Chd6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001221	transcription cofactor binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0008094	DNA-dependent ATPase activity
GO:0016787	hydrolase activity
GO:0016817	hydrolase activity, acting on acid anhydrides

Biological Process

GO:0006200	ATP catabolic process
GO:0006351	transcription, DNA-templated
GO:0016568	chromatin modification
GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

Cellular Component

GO:0005654	nucleoplasm
GO:0005665	DNA-directed RNA polymerase II, core complex

Protein Structure and Domains

PDB ID

MGI:1918639

InterPro

IPR000330 SNF2-related
IPR000953 Chromo domain/shadow
IPR001650 Helicase, C-terminal
IPR006576 BRK domain
IPR006935 Helicase/UvrB domain
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR016197 Chromo domain-like
IPR023780 Chromo domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF07533
PF04851
PF00270
PF00385

PRINTS

PIRSF

SMART

SM00298
SM00490
SM00592
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A3KFM7