InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ift52

Summary

InnateDB Protein

IDBP-211827.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ift52

Protein Name

intraflagellar transport 52 homolog (Chlamydomonas)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018002

InnateDB Gene

IDBG-211825 (Ift52)

Protein Structure

UniProt Annotation

Function

Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. {ECO:0000269PubMed:19253336}.

Subcellular Localization

Cell projection, cilium {ECO:0000269PubMed:19253336}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001841	neural tube formation
GO:0001947	heart looping
GO:0007224	smoothened signaling pathway
GO:0007368	determination of left/right symmetry
GO:0009953	dorsal/ventral pattern formation
GO:0042073	intraciliary transport
GO:0042733	embryonic digit morphogenesis
GO:0050680	negative regulation of epithelial cell proliferation
GO:0060271	cilium morphogenesis
GO:0070613	regulation of protein processing

Cellular Component

GO:0005813	centrosome
GO:0005929	cilium
GO:0030992	intraciliary transport particle B
GO:0032391	photoreceptor connecting cilium
GO:0036064	ciliary basal body
GO:0044292	dendrite terminus
GO:0097542	ciliary tip
GO:0097546	ciliary base