InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Becn1

Summary

InnateDB Protein

IDBP-212057.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Becn1

Protein Name

beclin 1, autophagy related

Synonyms

4921513J16Rik; 5430417M23Rik; Atg6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040094

InnateDB Gene

IDBG-212053 (Becn1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 65 interaction(s) predicted by orthology.

Experimentally validated
Total	36 [view]
Protein-Protein	36 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	65 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006914	autophagy
GO:0007040	lysosome organization
GO:0008285	negative regulation of cell proliferation
GO:0016239	positive regulation of macroautophagy
GO:0048666	neuron development
GO:0050435	beta-amyloid metabolic process
GO:0050790	regulation of catalytic activity
GO:0051707	response to other organism

Cellular Component

GO:0005737	cytoplasm
GO:0005802	trans-Golgi network
GO:0005856	cytoskeleton
GO:0016020	membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0043234	protein complex
GO:0045335	phagocytic vesicle

Protein Structure and Domains

PDB ID

MGI:1891828

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9QAM0

UniProt Splice Variant

Entrez Gene

56208

UniGene

Mm.400378

RefSeq

MGI ID

MGI Symbol

Becn1

OMIM

CCDS

HPRD

IMGT

EMBL

AL590969

GenPept