InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: B4GALT6

Summary

InnateDB Protein

IDBP-2122.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

B4GALT6

Protein Name

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

Synonyms

B4Gal-T6; beta4Gal-T6;

Species

Homo sapiens

Ensembl Protein

ENSP00000306459

InnateDB Gene

IDBG-2120 (B4GALT6)

Protein Structure

UniProt Annotation

Function

Required for the biosynthesis of glycosphingolipids. {ECO:0000269PubMed:1551920, ECO:0000269PubMed:3099851}.

Subcellular Localization

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.

Disease Associations

Tissue Specificity

High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008378	galactosyltransferase activity
GO:0016757	transferase activity, transferring glycosyl groups
GO:0046872	metal ion binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0018146	keratan sulfate biosynthetic process
GO:0018279	protein N-linked glycosylation via asparagine
GO:0030203	glycosaminoglycan metabolic process
GO:0042339	keratan sulfate metabolic process
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process