Version 5.4
Mus musculus Protein: Slc25a22
Summary
InnateDB Protein IDBP-212214.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc25a22
Protein Name solute carrier family 25 (mitochondrial carrier, glutamate), member 22
Synonyms 1300006L01Rik; AI060884; Gc1;
Species Mus musculus
Ensembl Protein ENSMUSP00000019226
InnateDB Gene IDBG-212212 (Slc25a22)
Protein Structure
UniProt Annotation
Function Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+) (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005313 L-glutamate transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0015813 L-glutamate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1915517
InterPro IPR002067 Mitochondrial carrier protein
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain
PFAM PF00153
PRINTS PR00926
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D6M3
PhosphoSite PhosphoSite-Q9D6M3
TrEMBL V9GWS2
UniProt Splice Variant
Entrez Gene 68267
UniGene
RefSeq NP_080922
MGI ID
MGI Symbol Slc25a22
OMIM
CCDS CCDS22013
HPRD
IMGT
EMBL AC102547 AK010193 AK046874 AK048389 AK049313 AK155276 AK162400 BC037949 BC050887
GenPept AAH37949 AAH50887 BAB26760 BAC32903 BAC33318 BAC33676 BAE33159 BAE36895

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca