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InnateDB Protein
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IDBP-212375.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Etv4
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Protein Name
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ets variant gene 4 (E1A enhancer binding protein, E1AF)
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Synonyms
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AW414408; Pea-3; Pea3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000017868
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InnateDB Gene
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IDBG-212373 (Etv4)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
4
[view]
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| Protein-Protein |
4
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
11 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0000978
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RNA polymerase II core promoter proximal region sequence-specific DNA binding
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GO:0000981
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sequence-specific DNA binding RNA polymerase II transcription factor activity
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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| Biological Process |
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0008045
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motor neuron axon guidance
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GO:0033600
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negative regulation of mammary gland epithelial cell proliferation
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GO:0045893
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positive regulation of transcription, DNA-templated
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GO:0048863
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stem cell differentiation
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GO:0060444
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branching involved in mammary gland duct morphogenesis
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GO:0060762
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regulation of branching involved in mammary gland duct morphogenesis
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| Cellular Component |
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| PDB ID |
MGI:99423
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| InterPro |
IPR000418
Ets domain
IPR006715
PEA3-type ETS-domain transcription factor, N-terminal
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| PFAM |
PF00178
PF04621
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| PRINTS |
PR00454
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| PIRSF |
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| SMART |
SM00413
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
A2A5C3
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| UniProt Splice Variant |
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| Entrez Gene |
18612
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| UniGene |
Mm.5025
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| RefSeq |
XP_006532521
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| MGI ID |
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| MGI Symbol |
Etv4
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL591436
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| GenPept |
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Version 5.4