InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Etv4

Summary

InnateDB Gene

IDBG-212373.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Etv4

Gene Name

ets variant gene 4 (E1A enhancer binding protein, E1AF)

Synonyms

AW414408; Pea-3; Pea3

Species

Mus musculus

Ensembl Gene

ENSMUSG00000017724

Encoded Proteins

IDBP-212375

ets variant gene 4 (E1A enhancer binding protein, E1AF)

IDBP-267227

ets variant gene 4 (E1A enhancer binding protein, E1AF)

IDBP-619970

ets variant gene 4 (E1A enhancer binding protein, E1AF)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175832:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:101769742-101785371

Strand

Reverse strand

Band

Transcripts

ENSMUST00000017868	ENSMUSP00000017868
ENSMUST00000107176	ENSMUSP00000102794
ENSMUST00000132040
ENSMUST00000129160
ENSMUST00000131862
ENSMUST00000129995
ENSMUST00000140970
ENSMUST00000149099
ENSMUST00000131117
ENSMUST00000137179
ENSMUST00000154512
ENSMUST00000164750	ENSMUSP00000129261

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0008045	motor neuron axon guidance
GO:0010628	positive regulation of gene expression
GO:0033600	negative regulation of mammary gland epithelial cell proliferation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048863	stem cell differentiation
GO:0060444	branching involved in mammary gland duct morphogenesis
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000175832

View Gene Order

ENSBTAG00000008333

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

INOH

PID NCI

lkb1_pathway

LKB1 signaling events

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.5025

RefSeq

NM_008815 XM_006532458 XM_006532459 XM_006532460 XM_006532461 XM_006532462 XM_006532464 XM_006532465 XM_006532466

OMIM

CCDS

CCDS48937

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas