InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ctsa

Summary

InnateDB Protein

IDBP-212383.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ctsa

Protein Name

cathepsin A

Synonyms

AU019505; PPCA; Ppgb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099382

InnateDB Gene

IDBG-212379 (Ctsa)

Protein Structure

UniProt Annotation

Function

Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.

Subcellular Localization

Lysosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004185	serine-type carboxypeptidase activity
GO:0005515	protein binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome