InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sost

Summary

InnateDB Protein

IDBP-212399.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sost

Protein Name

sclerostin

Synonyms

5430411E23Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001534

InnateDB Gene

IDBG-212397 (Sost)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0001503	ossification
GO:0009612	response to mechanical stimulus
GO:0030178	negative regulation of Wnt signaling pathway
GO:0030279	negative regulation of ossification
GO:0030514	negative regulation of BMP signaling pathway
GO:0031333	negative regulation of protein complex assembly
GO:0045893	positive regulation of transcription, DNA-templated
GO:0071374	cellular response to parathyroid hormone stimulus
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:2000054	negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification