Version 5.4
Mus musculus Protein: Tspan32
Summary
InnateDB Protein IDBP-212662.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tspan32
Protein Name tetraspanin 32
Synonyms Art-1; AW208513; BB235973; D7Wsu37e; Phemx; Tssc6;
Species Mus musculus
Ensembl Protein ENSMUSP00000009396
InnateDB Gene IDBG-212660 (Tspan32)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed exclusively in hematopoietic tissues. Expression detected in spleen, thymus, bone marrow and peripheral blood leukocytes but not in heart, brain, lung, liver, kidney or testis. {ECO:0000269PubMed:10950922}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007010 cytoskeleton organization
GO:0007229 integrin-mediated signaling pathway
GO:0007596 blood coagulation
GO:0007599 hemostasis
GO:0008285 negative regulation of cell proliferation
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0042832 defense response to protozoan
GO:0050688 regulation of defense response to virus
GO:0070527 platelet aggregation
Cellular Component
GO:0005622 intracellular
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0070442 integrin alphaIIb-beta3 complex
Protein Structure and Domains
PDB ID MGI:1350360
InterPro IPR008952 Tetraspanin, EC2 domain
IPR018499 Tetraspanin/Peripherin
PFAM PF00335
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JHH2
PhosphoSite PhosphoSite-
TrEMBL Q3U3L6
UniProt Splice Variant
Entrez Gene 27027
UniGene Mm.448095
RefSeq NP_001121552
MGI ID
MGI Symbol Tspan32
OMIM
CCDS CCDS52459
HPRD
IMGT
EMBL AC015800 AF175771 AF291425 AJ251788 AJ251835 AJ279791 AJ279792 AJ279793 AJ279794 AJ279795 AK154694 AY039000 CH466531
GenPept AAG27268 AAK83110 AAK84430 BAE32769 CAB94716 CAB94719 CAB94720 CAB94721 CAB94722 CAB94723 CAB94777 EDL18186

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca