Version 5.4
Mus musculus Gene: Tspan32
Summary
InnateDB Gene IDBG-212660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tspan32
Gene Name tetraspanin 32
Synonyms Art-1; AW208513; BB235973; D7Wsu37e; Phemx; Tssc6
Species Mus musculus
Ensembl Gene ENSMUSG00000000244
Encoded Proteins
IDBP-212662
tetraspanin 32
IDBP-212664
tetraspanin 32
IDBP-212666
tetraspanin 32
IDBP-269841
tetraspanin 32
IDBP-269843
tetraspanin 32
IDBP-269845
tetraspanin 32
IDBP-541330
tetraspanin 32
IDBP-534022
tetraspanin 32
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064201:
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:143005046-143019644
Strand Forward strand
Band F5
Transcripts
ENSMUST00000009396 ENSMUSP00000009396
ENSMUST00000075172 ENSMUSP00000074667
ENSMUST00000082008 ENSMUSP00000080668
ENSMUST00000105925 ENSMUSP00000101545
ENSMUST00000105924 ENSMUSP00000101544
ENSMUST00000105923 ENSMUSP00000101543
ENSMUST00000141186
ENSMUST00000145212 ENSMUSP00000116212
ENSMUST00000143512 ENSMUSP00000115344
ENSMUST00000154264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007010 cytoskeleton organization
GO:0007229 integrin-mediated signaling pathway
GO:0007596 blood coagulation
GO:0007599 hemostasis
GO:0008285 negative regulation of cell proliferation
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0042832 defense response to protozoan
GO:0050688 regulation of defense response to virus
GO:0070527 platelet aggregation
Cellular Component
GO:0005622 intracellular
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0070442 integrin alphaIIb-beta3 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064201
View Gene Order
ENSBTAG00000002702
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.28172 Mm.448095
RefSeq NM_001128080 NM_001128081 NM_001128082 NM_020286
OMIM
CCDS CCDS22037 CCDS52459 CCDS52460 CCDS52461
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca