Version 5.4
Mus musculus Protein: Kansl1
Summary
InnateDB Protein IDBP-213144.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kansl1
Protein Name RIKEN cDNA 1700081L11 gene
Synonyms 1700081L11Rik; 9430041J06Rik; mKIAA1267;
Species Mus musculus
Ensembl Protein ENSMUSP00000018556
InnateDB Gene IDBG-213142 (Kansl1)
Protein Structure
UniProt Annotation
Function As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
Biological Process
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0071339 MLL1 complex
Protein Structure and Domains
PDB ID MGI:1923969
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80TG1
PhosphoSite PhosphoSite-Q80TG1
TrEMBL B1AQV9
UniProt Splice Variant
Entrez Gene 76719
UniGene Mm.471044
RefSeq XP_006534516
MGI ID
MGI Symbol Kansl1
OMIM
CCDS CCDS48953
HPRD
IMGT
EMBL AK006970 AK037800 AK122484 AK153679 AK161514 AL593843 AL603709 BC025052 BC043121 BC053389 BC054752 BC079594
GenPept AAH25052 AAH43121 AAH53389 AAH54752 AAH79594 BAB24813 BAC65766 BAE20523 BAE32141 BAE36437 CAM14793

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca