Version 5.4
Mus musculus Gene: Kansl1
Summary
InnateDB Gene IDBG-213142.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kansl1
Gene Name KAT8 regulatory NSL complex subunit 1
Synonyms 1700081L11Rik; 9430041J06Rik; mKIAA1267
Species Mus musculus
Ensembl Gene ENSMUSG00000018412
Encoded Proteins
IDBP-213144
RIKEN cDNA 1700081L11 gene
IDBP-267640
RIKEN cDNA 1700081L11 gene
IDBP-267644
RIKEN cDNA 1700081L11 gene
IDBP-267646
RIKEN cDNA 1700081L11 gene
IDBP-531636
RIKEN cDNA 1700081L11 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120071:
This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:104333229-104468861
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000018556 ENSMUSP00000018556
ENSMUST00000069188
ENSMUST00000106977 ENSMUSP00000102590
ENSMUST00000106972 ENSMUSP00000102585
ENSMUST00000106971 ENSMUSP00000102584
ENSMUST00000134266 ENSMUSP00000116367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043995 histone acetyltransferase activity (H4-K5 specific)
GO:0043996 histone acetyltransferase activity (H4-K8 specific)
GO:0046972 histone acetyltransferase activity (H4-K16 specific)
Biological Process
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043984 histone H4-K16 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0005634 nucleus
GO:0071339 MLL1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000120071
View Gene Order
ENSBTAG00000012564
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_226917
HATs acetylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.136418 Mm.471044
RefSeq NM_001081045 XM_006534445 XM_006534446 XM_006534447 XM_006534449 XM_006534453
OMIM
CCDS CCDS48953
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca