Version 5.4
Mus musculus Protein: Stx16
Summary
InnateDB Protein IDBP-213419.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx16
Protein Name syntaxin 16
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000085218
InnateDB Gene IDBG-213413 (Stx16)
Protein Structure
UniProt Annotation
Function SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0016192 vesicle-mediated transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0000139 Golgi membrane
GO:0005730 nucleolus
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Protein Structure and Domains
PDB ID MGI:1923396
InterPro IPR000727 Target SNARE coiled-coil domain
IPR006011 Syntaxin, N-terminal domain
IPR010989 t-SNARE
PFAM PF05739
PF00804
PRINTS
PIRSF
SMART SM00397
SM00503
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BVI5
PhosphoSite PhosphoSite-Q8BVI5
TrEMBL Q8C0W8
UniProt Splice Variant
Entrez Gene 228960
UniGene Mm.487977
RefSeq NP_766263
MGI ID
MGI Symbol Stx16
OMIM
CCDS CCDS17147
HPRD
IMGT
EMBL AK029571 AK078110 AL669896 BC094436 BC138544
GenPept AAH94436 AAI38545 BAC26518 BAC37129 CAM25416

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca