Version 5.4
Mus musculus Protein: Adrm1
Summary
InnateDB Protein IDBP-213774.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adrm1
Protein Name adhesion regulating molecule 1
Synonyms 1110063P18Rik; 2510006J17Rik; AA408205; ARM-1; Arm1; AU043535; Gp110; Rpn13;
Species Mus musculus
Ensembl Protein ENSMUSP00000050076
InnateDB Gene IDBG-213772 (Adrm1)
Protein Structure
UniProt Annotation
Function Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. {ECO:0000269PubMed:15819879, ECO:0000269PubMed:18497827}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:15819879}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Present in all tissues examined (at protein level). {ECO:0000269PubMed:16815440, ECO:0000269PubMed:17139257}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001541 ovarian follicle development
GO:0007286 spermatid development
GO:0033081 regulation of T cell differentiation in thymus
GO:0042699 follicle-stimulating hormone signaling pathway
GO:0048477 oogenesis
GO:0048538 thymus development
GO:0060009 Sertoli cell development
GO:0060399 positive regulation of growth hormone receptor signaling pathway
GO:0060612 adipose tissue development
GO:0072520 seminiferous tubule development
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1929289
InterPro IPR006773 26S proteasome complex ubiquitin receptor, subunit Rpn13
PFAM PF04683
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JKV1
PhosphoSite PhosphoSite-Q9JKV1
TrEMBL
UniProt Splice Variant
Entrez Gene 56436
UniGene Mm.379082
RefSeq NP_062796
MGI ID 2Z59
MGI Symbol Adrm1
OMIM
CCDS CCDS17171
HPRD
IMGT
EMBL AF225959 AK075674 AK145474 AK145792 AK166878 AL663027 BC008974 BC031517
GenPept AAF33401 AAH08974 AAH31517 BAC35889 BAE26457 BAE26653 BAE39089 CAM16214

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca