InnateDB Protein
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IDBP-213888.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dido1
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Protein Name
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death inducer-obliterator 1
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Synonyms
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6720461J16Rik; D130048F08Rik; DATF-1; Datf1; DIO-1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000099344
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InnateDB Gene
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IDBG-213878 (Dido1)
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Protein Structure
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Function |
Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis (By similarity). Translocates to the nucleus after pro-apoptotic stimuli. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Expressed at intermediate levels.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
20 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1344352
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InterPro |
IPR001965
Zinc finger, PHD-type
IPR011011
Zinc finger, FYVE/PHD-type
IPR019787
Zinc finger, PHD-finger
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PFAM |
PF00628
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PRINTS |
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PIRSF |
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SMART |
SM00249
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TIGRFAMs |
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Modification |
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SwissProt |
Q8C9B9
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PhosphoSite |
PhosphoSite-Q8C9B9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23856
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UniGene |
Mm.490825
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RefSeq |
NP_001278361
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MGI ID |
1WEM
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MGI Symbol |
Dido1
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OMIM |
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CCDS |
CCDS17184
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HPRD |
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IMGT |
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EMBL |
AJ238332
AK032843
AK042474
AK044919
AK129117
AL732560
AY425951
AY425952
BC029110
BC044755
BC096662
BC138712
BC138713
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GenPept |
AAH29110
AAH44755
AAH96662
AAI38713
AAI38714
AAR84049
AAR84050
BAC28053
BAC31270
BAC32141
BAC97927
CAB48401
CAM27684
CAM27685
CAM27686
CAM27687
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