Version 5.4
Mus musculus Gene: Dido1
Summary
InnateDB Gene IDBG-213878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dido1
Gene Name death inducer-obliterator 1
Synonyms 6720461J16Rik; D130048F08Rik; DATF-1; Datf1; DIO-1
Species Mus musculus
Ensembl Gene ENSMUSG00000038914
Encoded Proteins
IDBP-213880
death inducer-obliterator 1
IDBP-213882
death inducer-obliterator 1
IDBP-213884
death inducer-obliterator 1
IDBP-213886
death inducer-obliterator 1
IDBP-213888
death inducer-obliterator 1
IDBP-534398
death inducer-obliterator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transcription factor involved in apoptosis. The encoded protein functions in cell cycle progression and plays a role in chromosomal stability. This protein regulates the self-renewal of embryonic stem cells. Disruption of this gene in mice causes symptoms similar to myelodysplastic/myeloproliferative diseases in humans. Mice lacking this gene show severely reduced fertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:180657964-180709999
Strand Reverse strand
Band H4
Transcripts
ENSMUST00000087517 ENSMUSP00000084794
ENSMUST00000037764 ENSMUSP00000048315
ENSMUST00000103057 ENSMUSP00000099346
ENSMUST00000103056 ENSMUSP00000099345
ENSMUST00000103055 ENSMUSP00000099344
ENSMUST00000103054
ENSMUST00000130986 ENSMUSP00000119689
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005819 spindle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101191
View Gene Order
ENSBTAG00000006002
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.253836 Mm.413255 Mm.490825
RefSeq NM_001291432 NM_001291433 NM_011805 NM_175551 NM_177852 XM_006500608 XM_006500609 XM_006500610 XM_006500611 XM_006500612 XM_006500613 XM_006500614 XM_006500615 XM_006500616
OMIM
CCDS CCDS17182 CCDS17183 CCDS17184
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca