Version 5.4
| Mus musculus Protein: Gga3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-214329.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gga3 | ||||||||
| Protein Name | golgi associated, gamma adaptin ear containing, ARF binding protein 3 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000019135 | ||||||||
| InnateDB Gene | IDBG-214327 (Gga3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2384159 | ||||||||
| InterPro |
IPR002014
VHS IPR004152 GAT IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain IPR008153 Clathrin adaptor, gamma-adaptin, appendage IPR008942 ENTH/VHS IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain IPR018205 VHS subgroup |
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| PFAM |
PF00790
PF03127 PF02883 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00809
SM00288 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8BMI3 | ||||||||
| PhosphoSite | PhosphoSite-Q8BMI3 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 260302 | ||||||||
| UniGene | Mm.119479 | ||||||||
| RefSeq | NP_766636 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Gga3 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS25641 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK031086 AK122212 AK132183 AL645470 | ||||||||
| GenPept | BAC27246 BAC65494 BAE21019 CAM23010 | ||||||||