InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Recql5

Summary

InnateDB Protein

IDBP-214372.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Recql5

Protein Name

RecQ protein-like 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021097

InnateDB Gene

IDBG-214370 (Recql5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000993	RNA polymerase II core binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0007067	mitotic nuclear division
GO:0032508	DNA duplex unwinding
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
GO:0051304	chromosome separation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016591	DNA-directed RNA polymerase II, holoenzyme
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

MGI:2156841

InterPro

IPR001650 Helicase, C-terminal
IPR004589 DNA helicase, ATP-dependent, RecQ type
IPR006935 Helicase/UvrB domain
IPR010716 RecQ helicase-like 5
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04851
PF06959
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VID5