InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aatk

Summary

InnateDB Protein

IDBP-214745.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aatk

Protein Name

apoptosis-associated tyrosine kinase

Synonyms

AATYK; aatyk1; mKIAA0641;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000067181

InnateDB Gene

IDBG-214739 (Aatk)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0006915	apoptotic process
GO:0007420	brain development
GO:0030517	negative regulation of axon extension
GO:0032482	Rab protein signal transduction
GO:0038083	peptidyl-tyrosine autophosphorylation
GO:0046777	protein autophosphorylation
GO:0051402	neuron apoptotic process

Cellular Component

GO:0005739	mitochondrion
GO:0005783	endoplasmic reticulum
GO:0044295	axonal growth cone
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

MGI:1197518

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt