InnateDB Protein
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IDBP-21753.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BAG5
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Protein Name
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BCL2-associated athanogene 5
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Synonyms
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BAG-5;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000299204
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InnateDB Gene
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IDBG-21751 (BAG5)
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Protein Structure
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Function |
Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. {ECO:0000250, ECO:0000269PubMed:20223214}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
43
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003103
BAG domain
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PFAM |
PF02179
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PRINTS |
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PIRSF |
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SMART |
SM00264
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UL15
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PhosphoSite |
PhosphoSite-Q9UL15
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TrEMBL |
G3V274
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UniProt Splice Variant |
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Entrez Gene |
9529
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UniGene |
Hs.641715
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RefSeq |
NP_001015048
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HUGO |
HGNC:941
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OMIM |
603885
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CCDS |
CCDS9982
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HPRD |
04862
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IMGT |
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EMBL |
AB020680
AF095195
AL139300
BC044216
BC050551
CH471061
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GenPept |
AAD16124
AAH44216
AAH50551
BAA74896
EAW81826
EAW81827
EAW81828
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