InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ARHGDIA

Summary

InnateDB Protein

IDBP-227541.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARHGDIA

Protein Name

Rho GDP dissociation inhibitor (GDI) alpha

Synonyms

GDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1;

Species

Homo sapiens

Ensembl Protein

ENSP00000383556

InnateDB Gene

IDBG-72684 (ARHGDIA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 101 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005094	Rho GDP-dissociation inhibitor activity
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Biological Process

GO:0006928	cellular component movement
GO:0007162	negative regulation of cell adhesion
GO:0007264	small GTPase mediated signal transduction
GO:0043066	negative regulation of apoptotic process
GO:0043547	positive regulation of GTPase activity
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0050770	regulation of axonogenesis
GO:0050771	negative regulation of axonogenesis
GO:0050772	positive regulation of axonogenesis
GO:0050790	regulation of catalytic activity
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0071526	semaphorin-plexin signaling pathway