Version 5.4
Homo sapiens Protein: CELA3B
Summary
InnateDB Protein IDBP-228627.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CELA3B
Protein Name chymotrypsin-like elastase family, member 3B
Synonyms CBPP; E1; EL-1; ELA3B;
Species Homo sapiens
Ensembl Protein ENSP00000383135
InnateDB Gene IDBG-281515 (CELA3B)
Protein Structure
UniProt Annotation
Function Efficient protease with alanine specificity but only little elastolytic activity.
Subcellular Localization
Disease Associations
Tissue Specificity Pancreas. Not detectable in keratinocytes. {ECO:0000269PubMed:10620133}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-P08861
TrEMBL
UniProt Splice Variant
Entrez Gene 23436
UniGene Hs.728752
RefSeq
HUGO HGNC:15945
OMIM
CCDS
HPRD 06498
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca