InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KCNJ8

Summary

InnateDB Protein

IDBP-23054.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNJ8

Protein Name

potassium inwardly-rectifying channel, subfamily J, member 8

Synonyms

KIR6.1; uKATP-1;

Species

Homo sapiens

Ensembl Protein

ENSP00000240662

InnateDB Gene

IDBG-23052 (KCNJ8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005242	inward rectifier potassium channel activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0015272	ATP-activated inward rectifier potassium channel activity
GO:0017098	sulfonylurea receptor binding

Biological Process

GO:0001822	kidney development
GO:0006813	potassium ion transport
GO:0007268	synaptic transmission
GO:0007507	heart development
GO:0009268	response to pH
GO:0010107	potassium ion import
GO:0032496	response to lipopolysaccharide
GO:0034765	regulation of ion transmembrane transport
GO:0042311	vasodilation
GO:0043330	response to exogenous dsRNA
GO:0045087	innate immune response (InnateDB)
GO:0051607	defense response to virus

Cellular Component

GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex
GO:0008282	ATP-sensitive potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030016	myofibril
GO:0042383	sarcolemma
GO:0043231	intracellular membrane-bounded organelle