InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTPN9

Summary

InnateDB Protein

IDBP-23458.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPN9

Protein Name

protein tyrosine phosphatase, non-receptor type 9

Synonyms

MEG2; PTPMEG2;

Species

Homo sapiens

Ensembl Protein

ENSP00000303554

InnateDB Gene

IDBG-23456 (PTPN9)

Protein Structure

UniProt Annotation

Function

Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus. {ECO:0000269PubMed:19167335}.

Subcellular Localization

Cytoplasm {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport
IPR001251 CRAL-TRIO domain
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR011074 CRAL/TRIO, N-terminal domain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00650
PF13716
PF03765

PRINTS

PR00700
PR00180

PIRSF

SMART

SM00194
SM00516
SM00404
SM01100

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt