Version 5.4
Homo sapiens Protein: MYCBP
Summary
InnateDB Protein IDBP-235090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYCBP
Protein Name c-myc binding protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000380702
InnateDB Gene IDBG-235088 (MYCBP)
Protein Structure
UniProt Annotation
Function May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
Subcellular Localization Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.
Disease Associations
Tissue Specificity Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 29 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007283 spermatogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99417
PhosphoSite PhosphoSite-Q99417
TrEMBL
UniProt Splice Variant
Entrez Gene 26292
UniGene Hs.632402
RefSeq NP_036465
HUGO HGNC:7554
OMIM 606535
CCDS CCDS431
HPRD 08406
IMGT
EMBL AB007191 AB451287 AB451419 AK311886 AL139260 BC008686 BT007109 D50692
GenPept AAH08686 AAP35773 BAA09338 BAA22408 BAG34827 BAG70101 BAG70233 CAI23050

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca